Donald F. Klein Early Career Investigator Award

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ADAA offers an annual award to an early career investigator for the best original research paper on neurobiology, psychopharmacology, psychosocial treatments, or experimental psychopathology of anxiety disorders and depression. This award is named for Donald F. Klein, MD (1928-2019), who revolutionized psychiatric thinking through his discovery in the early 1960s that imipramine, a recently developed psychotropic medication, was effective in blocking panic attacks.

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Congratulations to the 2023 Klein Awardee:

Emily Belleau, PhD

Dynamic Default Mode and Frontoparietal Network Alterations in Adolescents at High Familial Risk for Major Depressive Disorder and Prospective Associations with Stress Sensitivity

Dr. Belleau is a clinical psychologist and was recently promoted to Assistant Professor of Psychology in the Department of Psychiatry at McLean Hospital, Harvard Medical School. Her research program focuses on elucidating the neurobiological mechanisms underlying core cognitive and affective impairments in stress-related disorders, particularly Major Depressive Disorder (MDD) and Posttraumatic Stress Disorder (PTSD). To date, most of her work has focused on examining large-scale neural network dysregulations linked to maladaptive responses to aversive situations or contexts (i.e., negative valence systems) in these disorders. However, her most recent work has also incorporated examination of neural mechanisms underlying blunted responses to appetitive contexts (i.e., positive valence systems), and how negative and positive valence systems may interact to contribute to the development of stress-related disorders. To pursue these goals, she incorporates a multimodal approach including task-based and resting state functional neuroimaging, behavioral paradigms to probe cognitive and affective processes critically implicated in these disorders, comprehensive assessments of life stress histories, and ecological momentary assessment (EMA) to examine “real world” dynamic affective processes. Recently, she has received numerous internal and externally funded grants, including a Klingenstein Third Generation Postdoctoral Fellowship and a NIMH K23 Career Development Award (funded on the first round) to incorporate a developmental perspective to her line of research centering on adolescent depression.

The Donald F. Klein award is presented at ADAA's Annual Conference. This opportunity is open to members and nonmembers. Have a question email [email protected].

"The Donald F. Klein award offers a wonderful opportunity to highlight the work of promising young investigators and provides the logistical support for them to be able to share their work with the field more broadly.  I am grateful for the opportunity to share my work with others and to have expanded my academic connections." Sage E. Hawn, PhD, 2022 Klein Awardee

Please note that the Klein award does not provide a travel or hotel allowance. ADAA strongly suggests awardees book their stay at the conference hotel.

Thank you to our 2023 Klein Award Reviewers: Charles B. Nemeroff, MD, PhD and Victoria B Risbrough, PhD

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Award Components +

  • Complimentary registration to the ADAA Annual Conference (a $500 value)
  • A $500 cash award
  • Complimentary one year ADAA annual membership (up to $269 value)
  • Research paper will be automatically considered for acceptance in ADAA’s online scientific journal published by Elsevier - The Journal of Mood & Anxiety Disorders,TM and the article processing charge of $2,700 will be waived.
  • Award presented at the Annual Conference Award Ceremony on Saturday.
  • Opportunity to present research as a poster at the ADAA Annual Conference.
  • Featured profile on the ADAA website

Award Eligibility +

  • Restricted to investigators who have completed their terminal degree and are currently at a rank of assistant professor or below.
  • Individuals who are working to complete their degree are not eligible.
  • Willingness to host a professional webinar (recorded or live) within six months of winning the award on the research topic of the paper.
  • Must be first or senior author on the submitted paper, which must be original research on anxiety disorders, depression, and comorbid related disorders, focusing on neurobiology, psychosocial treatments, or experimental psychopathology.
  • The paper cannot be submitted or under review anywhere else from submission until notification about the award (including ADAA's Journal).
  • ADAA recognizes, supports, and values the inclusion of diverse groups, educational backgrounds, and views and encourages award applications from minority groups. ADAA also encourages interdisciplinary as well as international applicants.
  • ADAA Board Members and Scientific Council members are not eligible.

Application Requirements +

  • Headshot, biosketch, CV
  • Research Manuscript (include abstract, no page limit)
  • Letter of Reference from a previous or current mentor/advisor

About Donald F. Klein +

This award is named for Donald F. Klein, MD (1928-2019), who revolutionized psychiatric thinking through his discovery in the early 1960s that imipramine, a recently developed psychotropic medication, was effective in blocking panic attacks. Dr. Klein’s early contribution to the development of the DSM in large part gave birth to the modern branch of medical science dealing with the classification of disease of anxiety disorders. His early findings also heralded in the era of childhood anxiety disorders as biochemical disorders when he discovered that imipramine blocked childhood separation anxiety disorders.

In later years, Dr. Klein developed a compelling evolutionary-based hypothesis accounting for the etiology of panic disorders, which he terms “the false suffocation alarm theory of panic disorders.” His work remains relevant and topical to the present. Dr. Klein was the recipient of the 2005 ADAA Lifetime Achievement Award.